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EWPHE Study

O’Malley K, O’Brien et al. Antihypertensive Therapy in Patients Above Age Sixty. Sixth Interim Report of the European Working Party on High Blood Pressure in the Elderly (EWPHE). Hypertension in the Young and Old. Eds. G. Onesti, K.E. Kim. Grune and Stratton. New York. 1980.

O’Malley K, O’Brien et al. Antihypertensive Therapy in Patients Above Age Sixty. Fifth Interim Report of the European Working Party on High Blood Pressure in the Elderly (EWPHE). Current Concepts in Hypertension and Cardiovascular Disorders 1981;2:14-19.

O’Malley K, O’Brien et al.(EWPHE) Antihypertensive Therapy in Patients Above Age Sixty. Eighth Interim Report of the European Working Party on High Blood Pressure in the Elderly. Current Medical Research and Opinion 1982;8:5-18.

O’Malley K, O’Brien et al. Influence of Anti-hypertensive Therapy on Serum Cholesterol in Elderly Hypertensive Patients. (EWPHE) Acta Cardiologica 1982;37:235-244.

O’Malley K, O’Brien E, et al. Antihypertensive Therapy in Patients Above Sixty with Systolic Hypertension. (EWPHE) Clin Exper Hypertens Theory and Practice. 1982;A4(7):1151-1176.

European Working Party on High Blood Pressure in the Elderly.(EWPHE) Antihypertensive Therapy in Elderly Patients. Ninth Interim Report of the European Working Party on High Blood Pressure in the Elderly. Neth J Med 1984;27:165-170.

Amery A, Birkenhager W, O’Brien E, O’Malley K, et al.(EWPHE) Influence of Hypotensive Drug Treatment in Elderly Hypertensives: Study Terminating Events in the Trial Of the European Working Party on High Blood Pressure in the Elderly. J Hypertens 1985;3(Suppl 3):501-508.

O’Malley K, O’Brien E. European Working Party on High Blood Pressure in the Elderly (EWPHE). Initial: Objectives, protocol and organisation. Current Diagnosis and Management of Hypertensive Disease 1985

O’Malley K, O’Brien E, et al. (EWPHE) Antihypertensive Therapy in Elderly Patients. Tenth Interim Report of the Working Party on High Blood Pressure in the Elderly. Current Diagnosis and Management of Hypertensive Disease 1985.

Amery A, Birkenhager W, O’Brien E, O’Malley K, et al. Influence of Antihypertensive Drug Treatment on Morbidity and Mortality in Patients Over the Age of 60 Years. EWPHE Results: Sub-Group Analysis Based on Entry Stratification. J Hypertens 1986;4(Suppl 6):S642-S647.

O’Malley K, McCormack P, O’Brien E. Isolated Systolic hypertension: Data from the European Working Party on High Blood Pressure in the Elderly Study. J Hypertens 1988;6 (suppl 1):S105-S108.

Amery A, Birkenhager W, Bulpitt C, Clement D, de Leeuw P, Deruyttere M L, de Schaepdryver A, Dollery C, Fagard R, Fletcher A, Forrette F, Henry J-F, Koistinen A, Leonetti G, Nissinen A, O’Brien E, O’ Malley K, Pelemans W, Petrie J C, Terzoli L, Tuomilehto J, Williams B O. Diuretics – a risk in the long-term treatment of hypertensive patients? J Hypertens 1988;6:925-30.

Staessen J, Bulpitt C, Clement D, de Leeuw P, Fagard R, Fletcher A, Forette F, Leonetti G, Nissinen A, O’Malley K, Tuomilehto J, Webster J, Williams BO. Relation between mortality and treated blood pressure in elderly patients with hypertension: report of the European Working Party on High Blood Pressure in the Elderly. Brit Med J 1989;298:1552-6.

Staessen J, Amery A, Birkenhager W, Bulpitt C, Clement D, de Leeuw P, Deruyttere M, De Schaepdryver A, Dollery C, Fagard R, Fletcher A, Forette F, Forte J, Henry J F, Koistinen A, Leonetti G, Nissinen A, O’Brien E, O’Malley K, Pelemans W, Petrie J C, Strasser T K, Terzoli L, Thijs L, Tuomilehto J, Webster J, Williams B O. Is a high serum cholesterol is associated with a longer survival in elderly hypertensives? J Hypertens 1990;8:755-761.

Thijs L, Amery A, Birkenhager W, Bulpitt C, Clement D, de Leeuw P, De Schaepdryver A, Dollery C, Forette F, Henry J F, Koistinen A, Leonetti G, Nissinen A, O’Brien E, O’Malley K, Staessen J, Tuomilehto J, Webster J, Williams BO, Zanchetti A.. Age-related effects of placebo and active treatment in patients beyond the age of 60 years: the need for a proper control group. J Hypertens 1990;8:997-1002.

O’Malley K, O’Brien E, Cox J P. Further learnings from the European Working Party on high Blood Pressure in the Elderly (EWPHE) study: Focus on Systolic Hypertension. Cardiovascular Drugs and Therapy 1990;4:1249-1252.

Fletcher A, Amery A, Birkenhager W, Bulpitt C, Clement D, de Leeuw P, Deruyttere M, De Schaepdryver A, Dollery C, Fagard R, Forette F, Forte J, Henry J F, Koistinen A, Leonetti G, Lund_Johansen P, Nissinen A, O’Brien E, O’Malley K, Pelemans W, Petrie J, Staessen J, Terzoli L, Thijs L, Tuomilehto J, Webster J, Williams B O. Risks and benefits of the trial of the European Working Party on High Blood Pressure in the Elderly. J Hypertens 1991;9:225-230.

Thijs L for EWPHE. Age-related Hypotensive Effects of Placebo and Active Treatment in Patients Older Than 60 Years. Am J Med 1991;90(suppl 3A):24S-26S

Tuomilehto J for EWPHE. Body Mass Index and Prognosis in Elderly Hypertensive Patients: A Report from the European Working Party on High Blood Pressure in the Elderly. Am J Med 1991;90(suppl 3A):34S-41S

Fletcher A for EWPHE. Adverse Treatment Effects in the Trial of the European Working Party on High Blood Pressure in the Elderly. Am J Med 1991;90(suppl 3A):42S-44S

DeLeeuw P for EWPHE. Renal Function in the Elderly: Results from the European Working Party on High Blood Pressure in the Elderly. Am J Med 1991;90(suppl 3A):45S-49S

Staessen J for EWPHE. The Determinants and Prognostic Significance of Serum Uric Acid in Elderly Patients of the European Working Party on High Blood Pressure in the Elderly. Am J Med 1991;90(suppl 3A):50S-54S

Van Hoof R for EWPHE. Left Ventricular Hypertrophy in Elderly Hypertensive Patients: A Report from the European Working Party on High Blood Pressure in the Elderly. Am J Med 1991;90(suppl 3A):55S-59S

Staessen J for EWPHE. Mortality and Treated Blood Pressure in Patients of the European Working Party on High Blood Pressure in the Elderly. Am J Med 1991;90(suppl 3A):60S-61S

Fagard R for EWPHE. Serum Cholesterol Levels and Survival in Elderly Hypertensive Patients: Analysis of Data from the European Working Party on High Blood Pressure in the Elderly. Am J Med 1991;90(suppl 3A):62S-63S

Fagard RH, Staessen JA, Thijs L, Bulpitt CJ. For EWPHE Investigators. The European Working Party on High Blood Pressure in the Elderly (EWPHE) Trial. In: Clinical Trials in Hypertension, Ed: Black HR, Marcel Dekker Inc., New York, New York, USA, 2001,
pp 159-175 (ISBN 0-8247-0270-0).

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