Publications 2000 – 2009

Staessen JA, Emelianov D, Tjijs L, Celis H, Clement D, Davidson C, Gasowski J, Gil-Extremero B, Fogari R, Jaaskivi M, Lehtonen A, Nedogoda S, O’Brien E, Palatini P, Parati G, Salvetti A, Vanhanen H, Webster J, Fagard R em nome dos investigadores do Estudo Syst-Eur. Mapa nos idosos. In Montorizacao Ambulatorial de Pressao Arterial. Um Guia Pratico. Eds: L.S.M. Pereira and R. Henriques. Revinter. Rio de Janeiro. 2000. pp. 97-112.

Abstracts
Lyons S, Owens P, Fennessey F, Atkins N, Ryan D, O’Brien E. Comparison of pusle wave velocity measurement using ‘Colson’ arterial distensibility Complier and the ‘PWV’ Sphygmocor Pusle Wave System. J Human Hypertens 200;14;277

Mayett J, Patel P, Starmans-Kool M, Chapman N, Hughes AD, Thom SAMcG, Stanton AV. Is carotid artery intima-media thickening a reliable marker of early atherosclerosis? Amer J Hypertens 2000;13:192A

Chapman JN, Witt N, Stanton AV, Gau X, Thom SA, Hughes AD. A comparison of manual and 3 automated methods of determining retinal arteriolar diameters. Amer J Hypertens 2000;13:192A

Stanton AV, Chapman JN, Mayett J, Sever PS, Poulter NR, Hughes AD, Thom SA. Regression of intima media thickness and intima media area with blood pressure lowering by calcium channel blockade and angiotensin converting enzyme inhibition. Amer J Hypertens 2000;13:206A

Mayett J, Chapman JN, Hughes AD, Thom SAMcG, Stanton AV. Why do Afro-Caribbeans have a low incidence of ischaemic heart disease? Amer J Hypertens 2000;13:258A.

Spiering W, Rodriguez S, Atkins N, O’Brien E, de Leeuw. Association between dirnal blood pressure and angitensin-converting enzyme insertion/deletion polymorphism. J Hypertens 2000;18 (Suppl 4): S178.

Spiering W, Rodriguez Hernandez S, Kroon AA, Zwaan IM, Atkins N, Daemen E, O’Brien E, de Leeuw. Association between dirnal blood pressure and angitensin-converting enzyme insertion/deletion polymorphism. J Hypertens 2000;18 (Suppl 2): S146.

Voyaki S, Staessen J, Thijs L, Eistratopoulos A, Wang J, Birkenhager W, de Leeuw P, Rodicio J, Fagard R for the Systolic Hypertension in Europe (Syst-Eur) Trial investigators. J Hypertens 2000;18 (Suppl 2): S85.

O’Sullivan C, Duggan J, Lyons S, Thornton J, Lee M, O’Brien E. Hypertensive target organ damage in the very elderly. J Hypertens 2000;18 (Suppl 2): S51

General and educational
O’Brien E. White coat hypertension. Modern Medicine of Ireland. June 1999.23-28

O’Brien E. The ADAPTCentre at Beaumont Hospital. HeartWise 2000;3:16-20.

Houston M. We’re not identifying the hearts to watch. Irish Times 4.12.2000. p. 10

O’Brien E. The reality of the unreal. Beckett’s Ireland. Localmotives er et nettmagasin for samtidskunst og –kultur. Pinapple Publishing. www.localmotives.com. 21.12.2000

2001

Scientific papers
O’Brien E, Waeber B, Parati G, Staessen G, Myers MG. on behalf of the European Society of Hypertension Working Group on Blood Pressure Monitoring. Blood pressure measuring devices: recommendations of the European Society of Hypertension. BMJ 2001:322:531-536.

O’Brien E, Beevers G, Lip GHY. ABC of Hypertension. Part I. Sphygmomanometry: factors common to all techniques.BMJ 2001;322:981-985.

O’Brien E, Beevers G, Lip GHY. ABC of Hypertension. Part II. Conventional sphygmomanometry: Technique of auscultatory blood pressure measurement. BMJ 2001;322:1043-1047.

O’Brien E, Beevers G, Lip GHY. ABC of Hypertension. Part III. Automated sphygmomanometry: ambulatory blood pressure measurement. BMJ 2001;322:1110-1114.

O’Brien E, Beevers G, Lip GHY. ABC of Hypertension. Part IV. Automated sphygmomanometry: self blood pressure measurement. BMJ 2001;322:1167-1170.

Beevers G, Lip GYH, O’Brien E. ABC of Hypertension. The pathophysiology of hypertension. BMJ 2001;323:912-6

Voyaki SM, Staessen JA, Thijs L, Wang JG, Efstratopoulos AD, Birkenhager W, de Leeu PW, Leonetti G, Nachev C, Rodicio JL, Tuomilehto J, Fagard R, for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. J Hypertens 2001;19:511-519

Sever P, Dahlof B, Poulter N, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen S, McInnes G, Mehlsen J, Nieminen M, O’Brien E, Ostergen J. Rationale, design, methods and baseline demographic data of participants in the Anglo-Scandinavian Cardiac Outcomes Trial. J Hypertension 2001;19:1139-1147

Sever P, Dahlof B, Poulter N, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen S, McInnes G, Mehlsen J, Nieminen M, O’Brien E, Ostergen J. Anglo-Scandinavian Cardiac Outcomes Trial : a brief history, rationale and outline protocol. J Human Hypertens 2001;15 (Suppl 1):S1-2

Stanton A, Fitzgerald D, Hughes A, Mayet J, O’Brien E, Poulter N, Sever P, Shields D, Thom S. An intensive phenotyping study to enable the future examination of genetic influences on hypertension associated cardiovascular disease. J Human Hypertens 2001;15 (Suppl 1):S13-18

O’Brien E, McInnes GT, Stanton A, Thom S, Caulfield M, Atkins N. Ambulatory blood pressure monitoring and 24 hour blood pressure control as predictors of outcome in treated hypertensive patients. J Human Hypertens 2001;15 (Suppl 1):S47-51

O’Brien E, Gribben C, Stanton A, Atkins N, Lyons S. Left ventricular hypertrophy and silent ischemia: A pilot study to examine the relationship in hypertensive patients. J Human Hypertens 2001;15 (Suppl 1):S75-77

O’Neill H, O’Brien E, Stanton A, Hedditch K. The suitability of an automated blood pressure measuring device – the Omron HEM-705CP – in a large multicentre study: the ASCOT Study. J Human Hypertens 2001;15 (Suppl 1):S83-85

PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. Lancet 2001;358:1033-1041

O’Brien E. State of the market in 2001 for blood pressure measuring devices. Blood Press Monit 2001;6:171-176

O’Brien E. The need for specialized vascular units: the ADAPT approach. Seminars in Vascular Medicine 2001;1:133-136

O’Brien E. Validation Up-date. Blood Press Monit 2001;6:275-280

O’Brien E, van Montfrans G, Palatini P, Tochikubo O, Staessen J, Shirasaki O, Lipicky R, Myers M. Task Force I: Methodological aspects of blood pressure measurement. Sendai. Blood Press Monit 2001;6:313-315

Thijs L, O’Brien ET, Staessen JA for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Ambulatory and conventional pulse pressures and mean pressures as determinants of the Sokolow-Lyon ECG voltage index in older patients with systolic hypertension. Blood Press Monit 2001;6:197-202

Celis H, Thijs L, Staessen JA, Birkenhager WH, Bulpitt CJ, de Leeuw PW, Leonetti G, Nachev C, Tuomilehto J, Fagard RH for the Syst-Eur investigators. Interaction between nonsteroidal anti-inflammatory drug intake and calcium-channel blocker-based antihypertensive treatment in the Syst-Eur trial. J Human Hypertens 2001;15:613-618

Asmar RG, London GM, O’Rourke M, Safar M for the REASON Project coordinators and investigators. Improvement in Blood Pressure, Arterial Stiffness asn Wave Reflections With a Very-Low-Dose Perindopril/Indapamide Combination in Hypertensive Patients: A Comparison With Atenolol. Hypertension 2001:38:922-926

Stanton AV, Chapman JN, Mayet J, Sever PS, Poulter NR, Hughes AD, Thom SA. Effects of blood pressure lowering with amlodipine or lisinopril on vascular structure of the common carotid artery. Clin Sci (Lond). 2001;101:455-64.

Chapman N, Witt N, Gao X, Bharath AA, Stanton AV, Thom SA, Hughes AD. Computer algorithms for the automated measurement of retinal arteriolar diameters. Br J Ophthalmol 2001;85:74-9.

Editorials
Verdecchia P, Staessen JA, White WB, Imai Y, O’Brien ET. Properly defining white coat hypertension. Eur Heart J 2001;23:106-109

O’Brien E. Ambulatory blood pressure monitoring in primary care: a comment. Br J Cardiology 2001;8:531-535.

O’Brien E. Blood pressure measurement is changing! Heart 2001;85:3-5

O’Brien E, Staessen J. A plea for harmonising guidelines. International Journal of Cardiology 2001;79:129-132

O’Brien E. Editorial Note. Anglo-Scandinavian Cardiac Outcomes Trial. ASCOT. Main Protocol Summary and Sub-Study Protocols. J Human Hypertens 2001;15 (Suppl 1)S1

Letters
O’Brien E. Response to the Advisory Statement from the Council for High Blood
Pressure Research of the American Heart Association Advocating Retention of Mercury Sphygmomanometer. Hypertension 2001;38:e19-e20

O’Brien E.Blood pressure measurement. Authors’ reply. BMJ 2001;323:805-806

Book chapters
Staessen JA, Fagard RH, Thijs L, for Syst-Eur Onvestigators. The Systolic Hypertension in Europe Trial. In: Clinical Trials in Hypertension, Ed: Black HR, Marcel Dekker Inc., New
York, New York, USA, 2001, pp 313-356 (ISBN 0-8247-0270-0).

Fagard RH, Staessen JA, Thijs L, Bulpitt CJ. For EWPHE Investigators. The European Working Party on High Blood Pressure in the Elderly (EWPHE) Trial. In: Clinical Trials in
Hypertension, Ed: Black HR, Marcel Dekker Inc., New York, New York, USA, 2001,
pp 159-175 (ISBN 0-8247-0270-0).

O’Brien E. “Special blood pressure measuring devices”. In: Hypertension Manual. Ed. G. Mancia. Harcourt Brace & Co. Ltd. Pp173-184

Books and booklets
Beevers G, Lip GYH, O’Brien E. ABC of Hypertension. 4th Edition.2001. BMJ Books. London

Abstracts
Fagard R, Thijs L, Staessen JA on behalf of the Syst-Eur Trialists.A normal ambulatory blood pressure poorly predicts normalization of clinic pressure in hypertension. AJH 2001;14:21A.

Staessen JA, Thijs L, Celis H, Fagard R on behalf of the Syst-Eur Trialists. How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-up Study (Syst-Eur 2). AJH 2001;14:176A

Fletcher AE, Bulpitt CJ, Tuomilehto J, Thijs L, Staessen JA, Brown J, Bossini A, Kawecka-Jascziz P, Livinen P. Terzoli L, Vanska LO, Vanhanen H. On behalf of the Syst-Eur Trial Investigators. Quality of life in treated elderly patients with isolated systolic hypertension: results from the Syst-Eur Trial. J Hypertens 2001;19 (Suppl 2):S16

Forette ML, Seux L, Thijs L, Birkenhager WH, Fagard R, Staessen JA, Tuomilehto J, Webster J, Yodfat Y. On behalf of the Syst-Eur Investigators. Antihypertensive treatment prevents dementia: new evidence from the the Systolic Hypertension in Europe (Syst-Eur) Study. J Hypertens 2001;19 (Suppl 2):S183

Staessen JA, Thijs L, Celis H, Fagard R on behalf of the Systolic Hypertension in Europe (Syst-Eur) Investigators. How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-up Study (Syst-Eur 2). J Hypertens 2001;19 (Suppl 2):S103

Fagard R, Thijs L, Staessen JA on behalf of the Syst-Eur Trial Investigators. A normal ambulatory blood pressure poorly predicts normalization of clinic pressure in hypertension. J Hypertens 2001;19 (Suppl 2):S3

Beckett NS, Cooke JD, Fletcher AE, Bulpitt CJ. On behalf of the Hyvet Pilot Investigators. Number of patients achieving blood pressure targets in 12 months in the hypertension in the Very Elderly Trial (HYVET) Pilot. J Hypertens 2001;19 (Suppl 2):S103

Martinez-Perez ME, Hughes AD, Stanton AV, Thom SA, Chapman N, Bharath AA, Parker KH. Changes of retinal blood vessel tree topology in hypertension. (abstract) ASH poster presentation. Amer J Hypertens 2001.

General and educational
O’Brien E. Land mines. In Oxford Illustrated Companion to Medicine. Ed. S. Lock, J. Last and G. Dunea. Oxford University Press. 2001. pp.462-464

O’Brien E. A more holistic approach to cardiovascular disease. Forum 2001;18:46-48

O’Brien E. Holistic approach to hypertension. Nursing in the Community 2001;2:6-8

O’Brien E. Recent advances in ambulatory blood pressure measurement. Ir Med News 2001;May 28th.34

O’Brien E. Today’s role for ambulatory BP measurement. Prescriber 2001;12:95-104

O’Brien E. Hypertension Medicine. Edited by Michael A. Weber. Humana Press, Totowa, New Jersey. Pp. 461. Book Review. Ir J Clin Sci

O’Brien E. “Paint the smell of grass” Nevill Johnson (1911-1999). The Recorder. Journl of the American Irish Historical Society. 2001;14:61-70

O’Brien E. British Hypertension Recommendations on the Use and Interpretation of Ambulatory Blood Pressure Monitoring: Clinical Indications. Part I. Journal by Fax. 2001

O’Brien E. British Hypertension Recommendations on the Use and Interpretation of Ambulatory Blood Pressure Monitoring: Selecting a Monitoring Device. Part II. Journal by Fax. 2001

O’Brien E. Bodies Politic. Disease, Death and Doctors in Britain, 1650-1900. Roy Porter. Reakton Books. London. Pp. 328. 137 illus. ISBN 1 861 89 094 X. BMJ 2001;323:405

2002

Scientific papers
O’Brien E. Has conventional sphygmomanometry ended with the banning of mercury? Blood Press Monit 2002;7:37-40

O’Brien E, Pickering T, Asmar R, Myers M, Parati G, Staessen J, Mengden T, Imai Y, Waeber B, Palatini P with the statistical assistance of Atkins N and Gerin W on behalf of the Working Group on Blood Pressure Monitoring of the European Society of Hypertension. International protocol for validation of blood pressure measuring devices in adults. Blood Press Monit 2002;7:3-17

Staessen JA, Celis H, Thijs L, Den Hond E, Giot C, Leeman M, O’Brien E, Vandenhoven G, Fagard R on behalf of the THOP investigators Comparison of conventional and automated blood pressure measurements: interim anlysis of the THOP trial. Blood Press Monit 2002;7:61-62

Stanton AV, Mayet J, Chapman N, Foale RA, Hughes AD, Thom SAM. Ethnic differences in carotid and left ventricular hypertrophy. J Hypertens 2002:20; 1-5.

Kuznetsova T, Staessen J, Kawecka-Jaszcz K, Babeanu S, Casiglia E, Filipovsky J, Nachev C, Nikitin Y, Peleska, O’Brien E on behalf of the EPOGH investigators. Quality control of the blood pressure phenotype in the European Project on Genes in Hypertension. Blood Pressure Monit 2002:7:215-224

Gerin W, Schwartz AR, Schwartz JE, Pickering TG, Davidson KW, Bress J, O’Brien E, Atkins N. Limitations of current validtion protocols for home blood pressure monitors for individual patients. Blood Pressure Monit 2002:7:313-318

Kelly LA, Carroll P, McCormack P, O’Neill D.Timing of hospital presentation and delays in assessment in acute stroke. J Ir Coll Phys Surg 2002; 31: 73-76.

Starmans-Kool MJ, Stanton AV, Zhao S, Xu YX, Thom SAM, Hughes AD.Measurement of hemodynamics in human carotid artery using ultrasound and computational fluid dynamics. J Appl Physiol 2002; 92: 957-61.

O’Brien E. Recommendations for devices for measuring ambulatory blood pressure based on validation evidence. Nefrologia 2002;xxii (Suppl 3):3-6

Syst-Eur Trial Publications
Wingfield D, Cooke J, Thijs L, Staessen J, Fletcher A, Fagard R, Bulpitt CJ on behalf of the Syst-Eur Investigators. Terminal digit and single number preference in the Syst-Eur trial: influence of quality control. Blood Press Monit 2002;7:169-177

Staessen JA, Thijs L, O’Brien E, Bulpitt C, de Leeuw P, Fagard R, Nachev C, Palatini P, Parati G, Tuomilehto J, Webster J, Safar M.for the Syst-Eur Trial Investigators. Ambulatory Pulse Pressure as Predictor of Outcome in Older Patients With Systolic Hypertension. Am J Hypertens 2002;15:835-843

Fletcher AE, Bulpitt CJ, Thijs L, Tuomilehto J, Antikainen R, Bossini A, Brown J, Duggan J, Kawecka-Jaszez K, Kivinen P, Sarti C, Terzoli L, Staessen JA, on behalf of the Syst-Eur Trial Investigators. Quality of life on randomised treatment for isolated systolic hypertension: results from the Syst-Eur Trial. J Hypertens 2002;20:2069-2079

Palatini P, Thijs L, Staessen JA, Fagard R, Bulpitt CJ, Clement D, de Leeuw PW, Jääskivi M, Leonetti G, Nachev C, O’Brien ET, Parati G, Rodicio JL, Roman E, Sarti C, Tuomilehto J. Predictive value of clinic and ambulatory heart rate for mortality in elderly subjects with systolic hypertension. Arch Intern Med 2002;162:2313-21

Forette F, Seux ML, Staessen JA, Thijs L, Babarskiene MR, Babeanu S, Bossini A, Fagard R, Gil-Extremera B, Laks T, Kobalava Z, Sarti C, Tuomilehto J, Vanhanen H, Webster J, Yodfat Y, Birkenhager WH. The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Arch Intern Med 2002;162:2046-52

De Leeuw PW, Thijs L, Birkenhager WH, Voyaki SM, Efstratopoulos AD, Fagard RH, Leonetti G, Nachev C, Petrie JC, Rodicio JL, Rosenfeld JJ, Sarti C, Staessen JA. Prognostic significance of renal function in elderly patients with isolated systolic hypertension: results from the Syst-Eur trial. J Am Soc Nephrol. 2002 ;13:2213-22

Staessen JA, Thijs L, Celis H, Gasowski J, Wang JG, Fagard RH. Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients–evidence from the Systolic Hypertension in Europe Trial. S Afr Med J 2001;91:1060-8

Bulpitt CJ, Beckett NS, Fletcher AE, Thijs L, Staessen JA, Dumitrascu DL, Forette F, Leonetti G, Nachev C, Tuomilehto J, Fagard RH. Withdrawal from treatment in the Syst-Eur Trial. J Hypertens 2002;20:339-46

Thijs L, Staessen JA, Beleva S, Birkenhager WH, Bulpitt CJ, Celis H, Fletcher AE, Kermova R, Leonetti G, Laks T, Mantov S, Nachev C, Sarti C, Tuomilehto J, Fagard RH. How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2). Curr Control Trials Cardiovasc Med 2001;2:298-306

Celis H, Thijs L, Staessen JA, Birkenhager WH, Bulpitt CJ, de Leeuw PW, Leonetti G, Nachev C, Tuomilehto J, Fagard RH. Interaction between nonsteroidal anti-inflammatory drug intake and calcium-channel blocker-based antihypertensive treatment in the Syst-Eur trial. J Hum Hypertens. 2001;15:613-8.

Editorials
Stolarz K, Staessen JA, O’Brien E Night-tine blood pressure – dipping into the future? J Hypertens 2002;20:2131-2133

Letters
O’Brien E and Atkins N on behalf of the Working Group of the Working Group on Blood Pressure Monitoring of the European Society of Hypertension. The “International Protocol”: More Insight or More Arithmetic? J Blood Pressure Monit 2002;5:290-291

Book chapters
Staessen JA, Fagard R, Thijs L, Celis H, Arabidze GG, Babarskiene M-R, Babeanu S, Birkenhager W, Bulpitt C, de Leeuw P, Dollery CT, Fletcher A, Forette F, Kocemba J, Laks T, Leonetti G, Nachev C, O’Brien E, Petrie JC, Rodicio JL, Rosenfeld J, Tuomilehto J, Vanhanen H, Webster J, Yodfat Y, Zanchetti A for the Systolic-Hypertension in Europe (Syst-Eur) Trial Investigators. The Systolic Hypertension in Europe Trial. In: Clinical Trial Review of Hypertension Therapy. Ed.Henry Black. US. 2002.

Abstracts
Clement DL, De Buyzere M, DeBacquer D, De Leeuw P, Duprez DA, Fagard R, Gheeraert P, O’Brien E for the OvA Investigators. (Abstract) Am J Cardiol 2002;35 (Suppl A):243A

Staessen JA, Den Hond E, Celis H, Giot C, Keary L, Leeman M, O’Brien E, Vandenhoven G, Fagard R on behalf of the THOP investigators. Self-measurement of blood pressure as an alternative to ambulatory monitoring for the diagnosis of white coat hypertension. AJH 2002:15(Part 2 of 2);4A

Stanton A, Barton J, Jennsen C, Bobillier A, Mann J, O’Brien E. Dose response antihypertensive efficacy of aliskiren (SPP 100), an orally active rennin inhibitor. AJH 2002:15(Part 2 of 2);56A

Staessen JA, Thijs L, O’Brien E, Bulpitt CJ, deLeeuw PW, Fagard R, Nachev C, Palatini P, Parati G, Tuomilehto J, Webster J, Safar ME for Syst-Eur. Ambulartoy blood pressure – not mean pressure determines outcome in older patients with systolic hypertension. J Hypertens 2002:20(suppl 4);S74

Stanton A, Ghiuzeli C, Chapman N, Hughes A, Thom S. Human retinal arteriolar dilatation occurs with blood pressure lowering with amlodipine but not with lisinopril. J Hypertens 2002:20(suppl 4);S73

DeLuca N, Safar ME on behalf of the International Coordination Group Asmar R, Battegay E, Benetos A, De Leeuw P, Duprez D, Fitzgerald D, Hedner T, Hitzenberger G, London G, Mallion JM, O’Brien E, Olivier JP, O’Rourke MF, Polonia J, Rahn KH, Romero R, Sever P, Tomarco B. J Hypertens 2002:20(suppl 4);S164

Den Hond E, Celis H, Fagard R, Giot C, Keary L, Leeman M, O’Brien ET, Vandenhoven G, Staessen JA. Comparison of conventional and automated blood pressure measurements: interim analysis of the THOP Tial. J Hypertens 2002:20(suppl 4);S228

Stojanovic M, Stanton A, Lyons S, Atkins N and O’Brien ET. Patterns of age-related changes in ambulatory blood pressure parameters: Phase II of the Allied Irish Bank Study. J Hypertens 2002:20(suppl 4);S231

Celis H, Staessen JA, Thijs L, Buntinx F,De Buyzere M, Den Hond E, Fagard RH and O’Brien ET. Cardiovascular risk in white-coat and sustained hypertensive patients. J Hypertens 2002:20(suppl 4);S256

MacMahon S on behalf of the PROGRESS Collaborative Group. PROGRESS Global Results. J Hypertens 2002:20(suppl 4);S339

Tzourio C, Anderson C, Chapman N, Woodward M, Neal B, MacMahon S, Chalmers J on behalf of the PROGRESS Collaborative Group. PROGRESS in dementia and cognitive function in stroke patients. J Hypertens 2002:20(suppl 4);S339

Chalmers J on behalf of the PROGRESS Collaborative Group. Th PROGRESS results: comments and perspectives. J Hypertens 2002:20(suppl 4);S339

Donman JA for the PROGRESS Management Committee. PROGRESS Results: Implementation in Stroke Guidelines J Hypertens 2002:20(suppl 4);S339

Pringle EM, Phillips C, Thijs L, Davidson C, Parati G, Webster J, O’Brien E, Staessen JA. Night time systolic blood pressure variability as a risk factor for stroke J Hypertens 2002:20(suppl 4);S???.

General and educational
O’Brien E. Robert Graves. Dominic Corrigan. In Irish Innovators in Science and Technology. Eds:Charles Mollan, Willaim Davis, Brendan Finucane. Royal Irish Academy. 2002. p. 73 and p. 87.

O’Brien E, Bouchier-Hayes D. The solution to Ireland’s cardiovascular crisis: an integrated management strategy using a common database. Modern Medicine 2002;32:35-40

O’Brien E. Samuel Beckett and the weight of compassion. In: Borderlands: Essays on Literature and Medicine. Eds. Davis Coakley and Mary O’Doherty. A festchrift in honour of JB Lyons. 2002. pp. 141-150

O’Brien E. The importance of LIFE. Modern Medicine 2002;32:49

O’Brien E. “Paint the smell of grass”. Nevill Johnson (1911-1999). Pamphlet published by The Recorder. 2002. pp. 10

O’Brien E and Hall D. Nevill Johnson 1911-1999. Irish Arts Review October 2002

O’Brien E. ABPM is an indispensable technique. Irish Medical Times. 15 Nov 2002. p.32

2003

Scientific papers
Celis H, Staessen JA, Thijs L, Buntinx F, De Buyzere M, Den Hond E, Fagard R, O’Brien E on behalf of the Ambulatory Blood Pressure asn Treatment of Hypertenion (APTH) trial investigators. Cardiovascualr risk in white-coat and sustained hypertensive patients. Blood Pressure 2003;11:352-356

O’Brien E. Demise of the mercury sphygmomanometer and the dawning of a new era in blood pressure measurement. Blood Pressure Monit 2003;8:19-21

Den Hond E, Celis H, Vandenhoven G, O’Brien E, Staessen JA for the THOP investigators. Determinants of white-coat syndrome assessed by ambulatory blood pressure or self-measured home blood pressure. Blood Pressure Monit 2003;8:37-40

Den Hond E, Celis H, Fagard R, Keary L, Leeman M, O’Brien E, Vandenhoven G, Staessen JA on behalf of the THOP investigators. Self-measured versus ambulatory blood pressure in the diagnosis of hypertension. J Hypertens 2003;21:1-6

Stojanovic M, O’Brien E, Lyons S, Stanton A. Silent myocardial ischaemia in treated hypertensivs with and without left ventricular hypertrophy. Blood Pressure Monit 2003;8:45-51

Sever PS, Dahlöf B, Poulter NR, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O’Brien E, Östergren J, for the ASCOT investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003;361:1149-1158. Published online April 2, 2003: http://image.thelancet.com/extras/03art3046web.pdf

O’Brien E, Asmar R, Beilin L, Imai Y, Mallion J-M, Mancia G, Mengden T, Myers M, Padfield P, Palatinin P, Parati G, Pickering T, Redon J, Staessen J, Stergiou G, Verdecchia P on behalf of the European Society of Hypertension Working Group on Blood Pressure Monitoring. European Society of Hypertension recommendations for conventional, ambulatory and home blood pressure measurement. J Hypertens 2003;21:821–848

O’Brien E. Ambulatory Blood Pressure Monitoring in the Management of Hypertension. Heart 2003;89:571-576

O’Brien E. et al. Integrated Management of Cardiovascualr Risk. Report of a WHO Meeting. Geneva, 9-12 July 2002. Noncommunicable Diseases and Mental Health. World Health Organization. Pp. 1-35. Geneva. 2003

Guidelines Committee (Mancia G, Agabiti Rosei E, Cifkova CR, DeBacker G, Erdine S, Fagard R, Farsang C, Heagerty AM, Kawecka-Jaszcs K, W. Kiowski, Kjeldsen S, Luscher T, McInnes G, Mallion J-M, Mogensen CE, O’Brien E, Poulter NR, Priori SG, Rahn, KH, Rodicio JL, Ruilope LM, Safar M, Staessen JA, van Zwieten P,. Waeber B, Williams B, Zanchetti A, Zannad F) 2003 European Society of Hypertension–European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003:21:1011–1053

Guidelines Committee (Mancia G, Agabiti Rosei E, Cifkova CR, DeBacker G, Erdine S, Fagard R, Farsang C, Heagerty AM, Kawecka-Jaszcs K, W. Kiowski, Kjeldsen S, Luscher T, McInnes G, Mallion J-M, Mogensen CE, O’Brien E, Poulter NR, Priori SG, Rahn, KH, Rodicio JL, Ruilope LM, Safar M, Staessen JA, van Zwieten P,. Waeber B, Williams B, Zanchetti A, Zannad F) Practice Guidelines For Primary Care Physicians: 2003 ESH/ESC Hypertension Guidelines. J Hypertens 2003; 21: 1779-1786.

O’Brien E. Ambulatory blood pressure measurement is indispensable to good clinical practice. J Hypertens 2003;21(suppl 2):S11-S18

Clement DL, De Buyzere M, De Bacquer DA, de Leeuw PW, Duprez DA, Fagard RH, Gheeraert PJ, Missault LH, Braun JJ, Six RO, Van Der Niepen P, O’Brien E for the Office versus Ambulatory Blood Pressure (OvA) Study Investigators. Prognostic Value of Ambulatory Blood-Pressure Recordings in Patients with Treated Hypertension. New Eng J Med 2003.348.207-215

O’Sullivan C, Duggan J, Lyons S, Thornton J, Lee M, O’Brien E,. Hypertensive Target-Organ Damage in the Very Elderly. Hypertension. 2003:42:130-135

O’Brien E. A website for blood pressure measuring devices:dableducational.com. Blood Pressure Monit 2003, 8:177–180

Den Hond E, Staessen JA on behalf of the APTH and THOP investigators. Relation between left ventricular mass and systolic blood pressure at baseline in the APTH and THOP trials. Blood Press Monit 2003, 8:173–175

Dolan E, Atkins N, McClory S, Hinedi K, Sharifa S, McCormack P, Staessen J, Thijs L, Stanton A, O’Brien E. Ambulatory blood pressure measurement as a predictor of outcome in an Irish population: methodology for ascertaining mortality outcome. Blood Pressure Monit 2003, 8:143–145

O’Sullivan C, Duggan J, Atkins N, O’Brien E. Twenty-four-hour ambulatory blood pressure in community dwelling elderly men and women, aged 60–102 years. J Hypertens 2003, 21:1641–1647

Little MA, O’Brien E, Owens P, Holian J, Kenny S, Mee F, Walshe JJ. A Longitudinal Study of the Yield and Clinical Utility of a Specifically Designed Secondary Hypertension Investigation Protocol. Renal Failure 2003;25:709-717

Stanton A, Jensen C, Nussberger J, O’Brien E. Blood Pressure Lowereing in Essential Hypertension with an Oral Renin Inhibitor, Aliskiren. Hypertension 2003;42:1137-1143

O’Brien E, Atkins N, Murphy A, Lyons S. Validation of the ROSSMAX blood pressure measuring monitor according to the European Society of Hypertension International Protocol for Validation of Blood Pressure Measuring Devices in Adults. Blood Press Monit 2003;8: 261-265

O’Brien E, Atkins N, Murphy A, Lyons S. Validation of the TONOPORT V ambulatory blood pressure monitor according to the European Society of Hypertension International Protocol for Validation of Blood Pressure Measuring Devices in Adults. Blood Press Monit 2003;8:255-260

Bulpitt CJ, Beckett NS, Cooke J, Dumitrascu DL, Gil-Extremera, Nachev C, Nunes M, Peters R, Staessen J, Thijs L on behalf of the Hypertension in the Very Elderly (HYVET) Working Group. Results of the pilot study for the Hypertension in the Very Elderly Trial, J Hypertens 2003;21:2409-2417

Pringle E, Phillips C, Thijs L, Davidson C, Staessen JA, de Leeuw PW, Jaaskivi M, Nachev C, Parati G, O’Brien ET, Tuomilehto J, Webster J, Bulpitt CJ, Fagard R, on behalf of the Syst-Eur investigators. Systolic blood pressure variability as a risk factor for stroke and cardiovascular mortality in the elderly hypertensive population. J Hypertens 2003;21:2251-2257

Wood JM, Maibaum J, Rahuel J, Grütter MG, Cohen N-C, Rasetti V, Rüger H, Göschke R, Stutz S, Fuhrer W, Rigollier SP, Yamaguchi, Y, Cumin F, Baum H-P, Schnell C-R, Herold P, Mah R, Jensen C, O’Brien E, Stanton A, Bedigian MP. Structure-based design of aliskiren, a novel orally effective renin inhibitor with antihypertensive efficacy in human patients. Biochemical and Biophysical Research Communications (BBRC) 2003;308:698-705

Ho E, Stanton A. The role of the microcirculation in hypertension. Medicographia 2003; 25: 1-7.
Stanton AV Therapeutic potential of renin inhibitors in the management of cardiovascular disorders. Am J Cardiovasc Drugs 2003; 3: 389-94.

Stanton A. Potential of rennin inhibition in cardiovascular disease. JRAAS 2003;4:6-10

Editorials
Verdecchia P, O’Brien E, Pickering T, Staessen JA, Parati G, Myers M, Palatini P on behalf of the European Society of Hypertension Working Group on Blood Pressure Monitoring. When to suspect white coat hypertension? Statement from the Working Group on Blood Pressure Monitoring of the European Society of Hypertension. Am J Hypertens 2003;16:87-91

O’Brien E. The Working Group on Blood Pressure Monitoring of the European Society of Hypertension. Blood Pressure Monit 2003;8:17-18

O’Brien E. Ambulatory blood pressure measurement is indispensable to good clinical practice. Br J Cardiol 2003;10:110

O’Brien E. Ambulatory blood pressure measurement is now indispensable to the good clinical management of hypertension. Cardiovascular J South Africa 2003;14:157-163

O’Brien E. Blood pressure measurement in hypertension research. A workshop of the European Society of Hypertension. Blood Pressure Monit 2003;8:141-142

General and educational

O’Brien E. Farewell to the Journal of the Irish Colleges of Physicians and Surgeons. J Irish Colleges Phys Surg 2003;32:3-5

O’Brien E. Human rights and the making of a good doctor. In: Traditions, Values and Humanitarian Action. Ed. Kevin Cahill. International Humanitarian Series. Fordham Univeristy & Center for International Health and Cooperation. New York. 2003. pp. 136-152

O’Brien E. A review of recent guidelines on hypertension. Irish Medical News September 2003;44 & 52

Stanton A, O’Brien E. Lowering lipid levels in hypertension. Irish Medical News September.2003;36

2004

Scientific papers
PROGRESS Collaborative Group. Effects of a perindopril-based blood pressure lowering regimen on cardiac outcomes among patients with cerebrovascular disease. European Heart J 2003;24:475-484

Fagard R, Staessen JA, Thijs L, Bulpitt CJ, Clement D, deLeeuw P, Jaaskivi M, Mancia G, O’Brien E, Palatini P, Tuomilehto J, Webster J. Relationship between ambulatory blood pressure and follow-up clinic blood pressure in elderly patients with systolic hypertension.J Hypertens 2004;22:81-87

Staessen JA, Den Hond E,Celis H, Fagard R, Keary L, Vandenhoven G, O’Brien ET, for the Treatment of Hypertension Based on Home or Office Blood Pressure (THOP) Trial Investigators. Antihypertensive Treatment Based on Blood Pressure Measurement at Home or in the Physician’s Office. A Randomized Controlled Trial. JAMA 2004;291:955-964

MaIlion J-M, Chamontin B, Asmar R, De Leeuw PW, O’Brien E, Fitzgerald D, Duprez D, O’Rourke MF, Rahn K-H, Romero R, Battegay E, Hitzenberger G, Safar ME on behalf of the Reason project. Twenty-Four-Hour Ambulatory Blood Pressure Monitoring Efficacy of Perindopril/Indapamide First-Line Combination in Hypertensive Patients. The REASON Study. Am J Hypertension 2004;17:245-251

Staessen JA, Thijs L, Fagard R, Celis H, Birkenhager WH, Bulpittc CJ, de Leeuw PW, Fletcher AE, Forette F, Leonetti G, McCormack P, Nachevi C, O’Brien E, Rodicio JL, Rosenfeld J, Sarti C, Tuomilehto J, Webster J, Yodfat Y, Zanchetti A for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial. J Hypertens 2004; 22:847-857

de Luca N, MaIlion J-M, O’Rourke MF, O’Brien E, Rahn K-H, Trimmarco B, Romero R, De Leeuw PE, Hitzenberger G, Battegay E, Duprez D, Sever P, Safar ME, on behalf of the REASON project. Regression of left ventricular mass in hypertensive patients treated with perindopril/indapamide as a first-line combination: The REASON echocardiography study. AJH.2004;17:660-667

O’Brien E, Atkins N. Can improved software facilitate the wider use of ambulatory blood pressure measurement in clinical practice? Blood Press Monit 2004;9:237-241

Den Hond E, Staessen JA, Celis H, Fagard R, Keary L, Vandenhoven G, O’Brien ET, for the Treatment of Hypertension Based on Home or Office Blood Pressure (THOP) Trial Investigators. Antihypertensive Treatment based on Home or Office Blood Pressure – the THOP trial. Blood Press Monit 2004;9:311-314

Dolan E, Stanton A, Atkins N, Den Hond E, Thijs L, McCormack P, Staessen J, O’Brien E. Determinants of White Coat Hypertension. Blood Press Monit 2004;9:307-310

Fagard RH, Staessen JA, Thijs L, Celis H, Birkenha¨ger WH,C Bulpitt CJ, de Leeuw PW, Leonetti G, Sarti, Tuomilehto J, Webster J, Yodfat Y, for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Prognostic Significance of Electrocardiographic Voltages and Their Serial Changes in Elderly With Systolic Hypertension. Hypertension. 2004;44:459-464.

Staessen JA, Den Hond E, Celis H, Fagard R, Keary L, Vandenhoven G, O’Brien ET, for the Treatment of Hypertension Based on Home or Office Blood Pressure (THOP) Trial Investigator. Trial finds adjusting antihypertensive drugs based on home measurement may not improve blood pressure control [Commentary by Kjeldsen SE, Reims HM, Mancia G]. Journal of Evidenced-Based Cardiovascular Medicine 2004; 8: 202-205.

N. Chapman M. Woodward. Effects of a Perindopril-Based Blood Pressure–Lowering Regimen on the Risk of Recurrent Stroke According to Stroke Subtype and Medical History: The PROGRESS Trial. Stroke 2004;35: 116 – 121

Rodgers A, Chapman N, Woodward M, Liu L-S, Colman S, Lee A, Chalmers J, MacMahon S, on behalf of the PROGRESS Collaborative Group. Perindopril-based blood pressure lowering in individuals with cerebrovascular disease: consistency of benefits by age, sex and region. J Hypertens 2004, 22:653–659

Celis H, Staessen J, Thijs L, Buntinx F, De Buyzere M, Den Hond E, Fagard R, O’Brien E. Cardiovasculair risico bij patienten met wittejashypertensie en constante hypertensie. Huisarts Nu 2004;33:281-285

de Luca N, Asmar RG, London GM, O’Rourke MF Safar ME, on behalf of the REASON Project investigators. Selective reduction of cardiac mass and central blood pressure on low-dose combination perindopril/indapamide in hypertensive subjects. J Hypertens 2004; 22:1623–1630

Editorials
Stergiou G, Mengden T, Padfield PL. Parati G, O’Brien E. Self monitoring of blood pressure at home, BMJ 2004;329:870-871

O’Brien E. What’s new in blood pressure measurement? A workshop of the European Society of Hypertension. Blood Press Monit 2004;9:281-282

Letters
Staessen JA, Den Hond E, O’Brien ET Guidelines for Home- and Office-Based Blood Pressure Monitoring. JAMA, 2004;291:2315-216

General and educational
O’Brien E, Stanton A. The RHASP Project. Medicine Weekly. 25 February 2004. 62-63

Dolan E, McCormack P. Management of hypertension in the elderly population. Medicine Weekly. 25 May 2004. 62

Stanton A, O’Brien E. Should Clinic or 24hr Ambulatory BP Monitoring Guide Physicians? International Proceedings. 3rd Asian-Pacific Congress of Hypertension 2004;21-27

O’Brien E. European Society of Hypertension guidelines on blood pressure measurement. Irish Medical News. 18th October 2004

O’Brien E. Misdiagnosing hypertension: the importance of ABPM in identifying white coat and masked hypertension. Forum 2004

O’Brien E. How useful is self monitoring of blood pressure at home. Forum 2004;4:17-18

Abstracts
Ho E, Rooney Cm, Harhen B, Sever P, Hughes A, Thom S, Fitzgerald D, Stanton A. Doubling of isoprostane formation in a large cohort of hypertensive patients despite optimal medical management. J Hypertens 2004;22 (suppl 1): 43S

Dolan E, Atkins N, McClory S, Hinedi K, Stanton A, McCormack P, Staessen J, Thijs L, O’Brien E. A protocol for ascertaining mortality outcome in the absence of a national identifier or common fields. J Hypertens 2004;22 (suppl 1): 51S

Moore N, Stojanovic M, Lyons S, O’Brien E, O’Brien J, Stanton A. A newly discovered polymorphisim in the rennin gene enhancer region is associated with elevated ambulatory BP levels in a large community population. J Hypertens 2004;22 (suppl 1): 178S

Al Aloud B, Fulton A, Ch ng E, O’Brien E, Stanton A. Acute effects of hyperoxia and hypercapnia on retinal arteriolar and venular diameters. J Hypertens 2004;22 (suppl 1): 186S

Silveira E, Beckett N, Peters R, Banya W, Gil-Exterema B, Nachev C, Chodrouski Z, Fletcher A, Bulpitt C. Anti-hypertensive treatment does not lead to an increase in postural hypotension in most elderly patients – Results from the HYVET Pilot Study. J Hypertens 2004;22 (suppl 1): 93S

Peters R. The assessment of the quality of life in the Hypertension in the Very Elderly (HYVET) Trial. J Hypertens 2004;22 (suppl 1): 96S

Peters R on behalf of the HYVET investigators. Change of cognitive function within the first year of entering the Hypertension in the Very Elderly Trial (HYVET). J Hypertens 2004;22 (suppl 1): 54S

E. Den Hond, H. Celis, R. Fagard, E. O’Brien, J.A. Staessen, for the THOP investigators. Diagnostic threshold to define hypertension by self-measured home blood pressure – the clinical evidence. ECR. Nice. October 2004.

2005

Scientific papers
Parati G, Mendis S, Abegunde D, Asmar R, Mieke S, Murray A, Shengelia B, Steenvoorden G, Van Montfrans G, O’Brien E. Recommendations for blood pressure measuring devices for office/clinic use in low resource settings. Blood Press Monit 2005;10:3-10

Sever PS, Dahlof B, Poulter NR, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O’Brien E, Ostergren J; ASCOT Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial–Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Drugs. 2004;64 Suppl 2:43-60

[O’Brien E and Mendis S. Co-chairs] Affordable Technology. Blood Pressure Measuring Devices for Low Resource Settings. WHO Publication. Geneva.2005.pp.32

O’Brien E, Asmar R, Beilin L, Imai Y, Mancia G, Mengden T, Myers M, Padfield P, Palatini P, Parati G, Pickering T, Redon J, Staessen J, Stergiou G, Verdecchia P on behalf of the European Society of Hypertension Working Group on Blood Pressure Monitoring. Practice guidelines of the European Society of Hypertension for clinic, ambulatory and self blood pressure measurement.J Hypertens 2005, 23:697–701

Dolan E, Stanton A, Thijs L, Hinedi K, Atkins N, McClory S, Den Hond E, McCormack P, Staessen JA, O’Brien E. Superiority of Ambulatory Over Clinic Blood Pressure Measurement in Predicting Mortality: The Dublin Outcome Study. Hypertension. 2005;46:156-161

Sever PS, Poulter NR, Dahlöf B, Wedel H, Collins R, Beevers G, Caulfield M, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O’Brien E, Ostergren J for the ASCOT investigators. Reduction in Cardiovascular Events With Atorvastatin in 2532 patients with type 2 diabetes.ASCOT-LLA. Diabetes Care 2005;28:1151-1157.

O’Brien E, Stanton A. Clinical Review: Shared care can help prevent heart disease. Forum 2005;22:33-35

Dahlöf B, Sever PS, Poulter NR, Wedel H, Beevers DG, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O´Brien E, Östergren J for the ASCOT investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomized controlled trial. Lancet. www.thelancet.com Published online September 4, 2005 DOI:10.1016/S0140-6736(05)67185-1. Lancet 2005:366:895-906.

Poulter NR, Wedel H, Dahlöf B, Sever PS, Beevers DG, Caulfield M, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O´Brien E, Östergren J, Pocock S for the ASCOT nvestigators. Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA) Lancet. www.thelancet.com Published online September 4, 2005 DOI:10.1016/S0140-6736(05)67186-3. Lancet 2005:366:907-913.

Sever PS, Poulter NR, Dahlöf B,Wedel H for the Anglo-Scandinavian Cardiac Outcomes Trial Investigators. Different Time Course for Prevention of Coronary and Stroke Events by Atorvastatin in the Anglo-Scandinavian Cardiac Outcomes Trial–Lipid-Lowering Arm (ASCOT-LLA). Am J Cardiol 2005;96[suppl]:39F–44F.

Staessen JA, Kuznetsova T, Accetor R, Bacchieri A, Brand E, Burnier M, Celis H, Citterios L, de Leeuw PW, Filipovsky J, Fournier A, Kawecka-Jaszcz k, Manunta P, Nikitin Y, O’Brien ET, Redon J, Thijs L, Ferrari P, Valentini G, Bianchi G, on behalf of the OASIS-HT Investigators. Ouabain and Adducin for Specific Intervention on Sodium in HyperTensio (OASIS-HT): design of a pharmacogenic dose-finding study. Pharmacogenomics 2005;6:755-775.

Lindgren P. Buxton M, Kahan T, Poulter NR, Dahloff B, Sever PS, Wedel H, Jonsson B on behalf of the ASCOT investigators. Cost-effectiveness of atorvastatin for the prevention of coronary and stroke events: an economic analysis of the Anglo-Scandinavian Cardiac Outcomes Trial—lipid-lowering arm (ASCOT-LLA). European Journal of Cardiovascular Prevention and Rehabilitation 2005:12:29–36

Dolan C, Shields DC, Stanton A, O’Brien E, Lambert DM, O’Brien JK, Treacy EP. Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians. BMC Medical Genetics 2005, 6:41 (2 December 2005)

Editorials
O’Brien E. Unmasking Hypertension. Hypertension 2005;45:481-482.

O’Brien E. From measurement to profiles, phenomena and indices: a workshop of the European Society of Hypertension.Blood Press Monit 2005:10:291-295.

O’Brien E. Whither blood pressure measurement? Am J Hypertens 2005;18: ??

Letters
Dolan E, O’Brien ET, Staessen JA. Letter Regarding Article by Sega et al, “Prognostic Value of Ambulatory and Home Blood Pressures Compared With Office Blood Pressure in the General Population”. Circulation 2005;112:e244-5; author reply e245-6.

Dolan E, Stanton A, O’Brien E, Staessen JA. Superiority of Ambulatory Over Clinic Blood Pressure Measurement. Hypertension 2005;45:e11-e12.

O’Rourke MF, Nichols WW, O’Brien E. Effects of Ramipril on Arterial Stiffness. Hypertension 2005;45:e14-e15

General and educational
O’Brien E. Striving for accuracy in blood pressure measurement in the clinic setting. Irish Medical News 2005; May 3:46-47

O’Brien E. The art of detecting hidden hypertension. Forum 2005;June:47-48

O’Brien E. ABPM: Your questions answered.Modern Medicine 2005;35:45.

O’Brien E, Stanton A. Less Heart Disease with Shared Care. Diabetes Professional 2005;24-26

O’Brien E. Foreword. Protecting Personal Health Information in Ireland; Law and Practice. Peter Lennon. Oak Tree Press. 2005.xi-xv

Abstracts
Dolan E, Stanton A, Thijs L, Atkins N, McCormack P, Staessen JA, O’Brien ET. Prognostic significance of the nocturnal decline in systolic blood pressure: Dublin mortality outcome study.J Human Hypertens 2005;19:826

Tapp R, Sharp A, Chaturvedi N, Stanton A, Mayet J, Hughes AD, Thom S. Effects of blood pressure lowering with beta-blockerþdiuretic-based therapy and calcium antagonist and angiotensin-converting enzyme inhibitor-based therapy on left ventricular diastolic function. J Human Hypertens 2005;19:827

Dolan E, Stanton A, Thijs L, Atkins N, McCormack P, Staessen JA, O’Brien ET. Ambulatory heart rate predicts cardiovascular and non-cardiovascular mortality: Dublin mortality outcome study. J Human Hypertens 2005;19:829

Poulter NR, Chang CL, Dahlof B, Sever PS, Wedel H for the ASCOT Investigors.The effect of doxazosin on blood pressure of subjects with treated but uncontrolled hypertension: evidence from the ASCOT trial. J Human Hypertens 2005;19:846

Dolan E, Thijs L, Atkins N, McCormack P, O’Brien E, Staessen JA, Stanton A Ambulatory arterial stiffness index (AAS), a novel measure of arterial stiffness, provides additional prediction of cardiovascular cardiovascular mortality. J Hypertens 2005;23 (suppl 2): S258

Li Y, Wang J-G, Dolan E, Gao P-J, Guo H-F, Nawrot T, Stanton AV, Zhu D-L, O’Brien E, Staessen JA. Ambulatory Arterial Stiffness Index Derived from 24-Hour Ambulatory Blood Pressure Monitoring. J Hypertens 2005;23 (suppl 2): S227

Dolan E, Stanton A, Thijs L, Hinedi K, Atkins N, McClory S, Den Hond E, McCormack P, Staessen JA, O’Brien E. Prediction of Cardiovascular Mortality by Ambulatory Blood Pressure Monitoring: The Dublin Outcome Study. J Hypertens 2005;23 (suppl 2): S136

De Buyzere M, Clement DL, De Bacquer DA for the OvAInvestigators. Prognostic Value of Ambulatory Blood-Pressure. New data of the OvA Study. J Hypertens 2005;23 (suppl 2): S146

2006

Scientific papers
Li Y, Wang J-G, Dolan E, Gao P-J, Guo H-F, Nawrot T, Stanton AV, Zhu D-L, O’Brien E, Staessen JA. Ambulatory Arterial Stiffness Index Derived from 24-Hour Ambulatory Blood Pressure Monitoring. Hypertension 2006;47:359-364

Dolan E, Thijs L, Li Y, Atkins N, McCormack P, McClory S, O’Brien E, Staessen JA, Stanton AV. Ambulatory Arterial Stiffness Index as a Predictor of Cardiovascular Mortality in The Dublin Outcome Study. Hypertension 2006;47:365-370

Dolan E, Li Y, Thijs L, McCormack P, Staessen JA, O’Brien E, Stanton A. Ambulatory arterial stiffness index: rationale and methodology. Blood Press Monit 2006:11:103–105

Li Y, Dolan E, Wang J-G, Thijs L, Zhu D-L, O’Brien E, et al. Ambulatory arterial stiffness index: determinants and outcome. Blood Press Monit 2006:11:107-110

Hansen TW, Staessen JA, Torp-Pedersen C, Rasmussen S, Li Y, Dolan E, Thijs L, Wang J-G, O’Brien E, Ibsen H, Jeppesen J. Ambulatory arterial stiffness index predicts stroke in a general population. J Hypertens 2006;24:000–000

The CAFÉ Investigators for the ASCOT Investigators Differential Impact of Blood Pressure Lowering drugs on Central Aortic Pressure and Clinical Outcomes – Principal Results of the Conduit Artery Function Evaluation (CAFE) study. Circulation 2006;113:1213-1225

O’Brien E. Aliskiren: a renin inhibitor offering a new approach for the treatment of hypertension. Expert Opinion on Investigational Drugs 2006;15:1269-1277

Sever P, Dahloff B, Poulter N, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen S, Kristinsson A, McInnes G, Mehlsen J, Nieminem M, O’Brien E, Ostergren J on behalf of the ASCOT Steering Committee Members. Potential synergy between lipid-lowering and blood-pressure-lowering in the Anglo-Scandinavian Cardiac Outcomes Trial. European Heart Journal 2006:27:2982–2988

O’Halloran AM, Stanton A, O’Brien E, Shields DC. The Impact on Coronary Artery Disease of Common Polymorphisms Known to Modulate Responses to Pathogens. Ann Hum Genetics 2006; 70,934–945

Arima H, Chalmers J, Woodward M, Anderson C, Rodgers A, Davis S, MacMahon S, Neal B for the PROGRESS Collaborative Group. Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial. J Hypertens 2006, 24:1201–1208

Books and booklets
Beevers GH, Lip DG, O’Brien E. ABC of Hypertension. 5th Edition. BMJ/Blackwell.2006.

Editorials
O’Brien E. Whither conventional blood pressure measurement? Am J Hypertens 2006;19:659

O’Brien E. Ambulatory Blood Pressure Measurement: A Trove of Hidden Gems. Hypertension 2006;48;364-365

Letters
Li Y, Wang J-G, Dolan E, O’Brien E, Thijs L, Nawrot T, Staessen J. Response to Correlating Ambulatory Blood Pressure Measurements With Arterial Stiffness: A Conceptual Inconsistency. Hypertension 2006;48;e109

General and educational
O’Brien E, Dolan E. Emerging role for nocturnal blood pressure. Cardiology Professional. Spring 2006 p. 1-2/

O’Brien E. Ascendency of angiotensin II receptor blocking drugs (ARBs) in the treatment of cardiovascular disease. Irish Medical News 2006.Feb. p 45.

O’Brien E. The pursuit of compassion. Irish Medical News 2006. March. p20.

O’Brien E. History of the Blood Pressure Unit at the Charitable Infirmary and Beaumont Hospital 1978-2006. Heartwise. Winter 2006. 12-18.

2007

Scientific papers
Boggia J, Li Y, Thijs L, Hansen TW, Kikuya M, Björklund-Bodegård K, Richart T, Ohkubo T, Kuznetsova T, Torp Pedersen C, Lind L, Ibsen H, Imai Y, Wang J, Sandoya E, O’Brien E, Staessen JA, on behalf of the International Database on Ambulatory blood pressure monitoring in relation to Cardiovascular Outcomes (IDACO) Investigators. Prognostic accuracy of day versus night ambulatory blood pressure: a cohort study. Lancet 2007;370:1219-1229

O’Brien E, Barton J, Nussberger J, Mulcahy D, Jensen C, Dicker P, Stanton A. Aliskiren provides antihypertensive efficacy and suppression of plasma rennin activity in combination with a thiazide diuretic, an angiotensin converting enzyme inhibito, or an angiotensin receptor blocker. Hypertension 2007;49:276-284

Chapman N, Dobson J, Wilson S, Dahlöf B, Sever PS, Wedel H, Poulter NR and on behalf of the Anglo-Scandinavian Cardiac Outcomes Trial Investigators. Effect of Spironolactone on Blood Pressure in Subjects With Resistant Hypertension. Hypertension 2007;49:839-84

Moore N, Dicker P, O’Brien JK, Stojanovic M, Conroy RM, Treumann A, O’Brien ET, Fitzgerald D, Shields D, Stanton AV. Renin Gene Polymorphisms and Haplotypes, Blood Pressure, and Responses to Renin-Angiotensin System Inhibition. Hypertension 2007;50;340-347

Hansen TW, Kikuya M, Thijs L, Björklund-Bodegård K, Kuznetsova T, Ohkubo T, Richart T,Torp-Pedersen C, Lind L, Jeppesen J, Ibsen H, Imai Y, Staessen JA on behalf of the IDACO Investigators. Prognostic superiority of daytime ambulatory over conventional blood pressure in four populations: a meta-analysis of 7030 individuals. J Hypertens 2007;25:1554-1564.

Kikuya M, Staessen JA, Ohkubo T, Thijs L, Metoki H, Asayama K, Obara T, Inoue R, Li Y, Dolan E, Hoshi H, Hashimoto J, Totsune K, Satoh H, Wang J-G, O’Brien E, Imai Y . Ambulatory Arterial Stiffness Index and 24-Hour Ambulatory Pulse Pressure as Predictors of Mortality in Ohasama, Japan. Stroke 2007 38: 1161 – 1166

Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Struijker Boudier HAJ, Zanchetti A, ESC Committee for Practice Guidelines (CPG): Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Dalby Kristensen S, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, ESH Scientific Council: Kjeldsen SE, Erdine S, Narkiewicz K, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Cifkova R, Dominiczak A, Fagard R, Heagerty AM, Laurent S, Lindholm LH, ManciaG, Manolis A, Nilsson PM, Redon J, Schmieder RE, Struijker-Boudier HAJ, Viigimaa H, Document Reviewers: Filippatos G, Adamopoulos S, Agabiti-Rosei E, Ambrosioni E, Bertomeu V, Clement D, Erdine S, Farsang C, Gaita D, Kiowski W, Lip G, Mallion J-M, Manolis AJ, Nilsson PM, O’Brien E, Ponikowski P, Redon J, Ruschitzka F, Tamargo J, van Zwieten P, Viigimaa M, Waeber B, Williams B, Zamorano JL. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007 28: 1462-1536. J Hypertens 2007:25;1105–1187

Thijs L, Hansen TW, Kikuya M,Bjorklund-Bodegard K, Li y, Dolan E, Tikhonoff V, Seidlerova J, Kuznetsova T, Stolarz K, Bianchi M, Richart T, Casigliag E, Malyutina S, Filipovsky J, Kawecka-Jaszcz K, Nikitin Y, Ohkubo T, Sandoya E, Wang J, Torp-Pedersen C, Lind L, Ibsen H, Imai Y, Staessen JA, O’Brien E and on behalf of the IDACO Investigators. The International Database of Ambulatory blood pressure in relation to Cardiovascular Outcome (IDACO): protocol and research perspectives. Blood Press Monit 2007, 12:255–262

Atkins N, O’Brien E. The DABL®Educational Trust device equivalence procedure. Blood Press Monit 2007:12:245–249

O’Brien E, Atkins N. State-of-the-market from the dableducational.org website. Blood Press Monit 2007;21:377-379

Dolan E, Staessen JA, O’Brien E. Data from the Dublin outcome study. Blood Press Monit 2007;21:401-403

O’Brien E. The circadian nuances of hypertension: a reappraisal of 24-h ambulatory blood pressure measurement in clinical practice. Ir J Med Sci 2007;176:55-63

Lindgren EP, Buxton M, Kahan T, Poulter NR, Dahloff B, Sever PS, Wedel H. Jonsson B on behalf of the ASCOT trial investigators. Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenololbased regimen. Heart 2008;94;4; originally published online doi:10.1136/hrt.2007.127217

Editorials
O’Brien E. Sleepers v non-sleepers.: a new twist in the dipper/non-dipper concept. Hypertension 2007;49:769-770

O’Brien E. Is the Case for ABPM as a Routine Investigation in Clinical Practice Not Overwhelming? Hypertension 2007;50:284-286

Staessen JA, O’Brien E. Progress in blood pressure measurement: a workshop of the European Society of Hypertension. Blood Press Monit 2007, 12:243–244

Staessen JA, O’Brien E. Will generic hypertension guidelines reduce the proliferation of directives? Heart 2007;93:775-777

Book chapters
O’Brien E, Atkins N. Validation and reliability of Blood Pressure Monitors. Ed. W. White. Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics. Humana Press Inc. US. 2007.Pp.97-132

Books and booklets
O’Brien E. Measurement of blood pressure. Part III. Ambulatory blood pressure measurement. In: ABC of Hypertension. Eds: DG Beevers, GH Lip, E O’Brien. Fifth Edition. BMJ/Blackwell Publishing. Oxford.UK.2007. pp.17-32.

Letters
Li Y, Wang J-G, Dolan E, O’Brien E, Hansen TW, Ibsen H, Kikuya M, Imai Y, Richart T, Thijs L, Staessen JA. Letter to the Editor: Response to Arterial Stiffness Index Is Not a Stiffness Parameter But a Ventriculo-Arterial Coupling Factor. Hypertension 2007;49;8-9; originally published online Jan 2, 2007; DOI: 10.1161/01.HYP.0000254948.10037.4a

Adiyaman A, Boggia J, Li Y, Wang J-G, O’Brien E, Richart T, Thijs L, Staessen JA. Dipping Deeper Into the Ambulatory Arterial Stiffness Index. Hypertension 2007;50;e59-e60

General and educational
O’Brien E. Managing blood pressure using ABPM. Ir Med News.2007.05.17.p.40

O’Brien E. Ignoring the evidence. Med Weekly.2007.08.22.p.52

O’Brien E. Management of Arterial Hypertension – 2007 Guidelines. Med Weekly.2007.08.22.pp.82-83

O’Brien E. Getting things under control. Cardiology Professional. Autumn 2007.pp.11-14.

O’Brien E. Stroke – a preventable disaster. Forum. Oct 2007. pp.43-45

O’Brien E. The Irish Heart Foundation in a Changing Society. Medicine Weekly 2007.p.34

2008

Scientific papers
O’Brien E. Ambulatory Blood Pressure Measurement. The Case for Implementation in Primary Care. Hypertension 2008;51;1435-1441. Originally published on-line March 24 2008 DOI:10.1161/ HYPERTENSIONAHA.107.100008.

Sever PS, Poulter NR, Dahlof B, Wedel H, Beevers G, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes G, Mehlsen J, Nieminen MS, O’Brien ET, Ostergren J on behalf of the ASCOT Investigators. The Anglo-Scandinavian Cardiac Outcomes Trial: lipid lowering arm: extended observations 2 years after trial closure. Eur Heart J 2008; 29:499–508

Burr LM, Dolan E, O’Brien EW, O’Brien ET, McCormack P. The value of ambulatory blood pressure in older adults: the Dublin outcome study. Age and Ageing 2008;37:201-206

Lia Y, Boggia J, Thijs L, Hansen TW, Kikuya M, Bjo rklund-Bodega rd K, Richart T, Ohkubo T, Kuznetsova T, Torp-Pedersen C, Lind L, Ibsen H, Imai Y, Wang J, Sandoya E, O’Brien E, Staessen JA, on behalf of the International Database on Ambulatory Blood Pressure Monitoring in relation to Cardiovascular Outcomes Investigators. Is blood pressure during the night more predictive of cardiovascular outcome than during the day? Blood Press Monit 2008;13:145-147

Wizner B, Dechering DG, Thijs L, Atkins N, Fagard R, O’Brien E, de Leeuw PW, Parati G, Palatini P, Clement D, Grodzicki T, Kario T, Staessen JA. Short-term and long-term repeatability of the morning blood pressure in older patients with isolated systolic hypertension. J Hypertens 2008;26:1328-1335

Parati G ,Stergiou GS, Asmar R, Bilo G, de Leeuw P, Imai Y, Kario K, Lurbe E, Manolis A, Mengden T, O’Brien E, Ohkubo T, Padfield P, Palatini P, Pickering T, Redon J, Revera M, Ruilope LM, Shennan A, Staessen JA, Tisler A, Waeber B, Zanchetti A, Mancia G on behalf of the ESH Working Group on Blood Pressure Monitoring. European Society of Hypertension guidelines for blood pressure monitoring at home: a summary report of the Second International Consensus Conference on Home Blood Pressure Monitoring. J Hypertens 2008, 26:1505–1530

Hansen TM, Thijs L, Boggia J, Li Y, Kikuya M, Björklund-Bodegård C, Richart T, Ohkubo T, Jeppesen J, Torp Pedersen C, Lind L, Sandoya E, Imai Y, Wang J, Ibsen H, O’Brien E, Staessen JA on behalf of the International Database on Ambulatory Blood Pressure in relation to Cardiovascular Outcomes Investigators. Prognostic Value of Ambulatory Heart Rate Revisited in 6928 Subjects From 6 Populations. Hypertension 2008;52:229-235

Omboni S, Costantini C, Pini C, Bulegato R, Manfellotto D, Rizzoni D, Palatini P, O’Brien E, Parati G. PA.NET International Quality Certification Protocol for Blood Pressure Monitors. Blood Press Monit. 2008;13:285-289

Dechering DG, van der Steen MS, Adiyaman A, Thijs L, Deinum J, Li Y, Dolan E, Akkermans RPM, Richart T, Hansen TW, Kikuya M,Wang J,O’Brien E, Thien T, Staessen JA. Reproducibility of the Ambulatory Arterial Stiffness Index in Hypertensive Patients. J Hypertens 2008;26:1993-2000

Östergren J, Poulter NR, Sever PS, Dahlöf B, Wedel H. Beevers G,Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O’Brien E for the ASCOT investigators. The Anglo-Scandinavian Cardiac Outcomes Trial: blood pressure-lowering limb: effects in patients with type II diabetes. J Hypertens 2008;26:2103-2111

Adiyaman A, Dechering D, Boggia J, Li Y, Hansen TW, Kikuya M, Björklund-Bodegård K, Richart T, Thijs L, Torp-Pedersen C, Ohkubo T, Imai Y, Sandoya E, Ibsen H, Wang J, Lind L, O’Brien E, Thien T, Staessen JA,on behalf of the International Database on Ambulatory blood pressure monitoring in relation to Cardiovascular Outcomes (IDACO) Investigators. The Ambulatory Arterial Stiffness Index Revisited in 7604 Subjects from 6 Populations. Hypertension. 2008;52:1038-1044

Staessen JA, Thijs L, Ohkubo T, Kikuya M, Richart T, Boggia J,Adiyaman A, Dechering DG, Kuznetsova T, Thien T, de Leeuw P, Imai Y, O’Brien E, Parati G. Thirty years of research on diagnostic and therapeutic thresholds for the self-measured blood pressure at home. Blood Press Monit 2008, 13:352–365

Beckett NS, Peters R, Fletcher AE, Staessen JA,Liu L, Dumitrascu D, Stoyanovsky V, Antikainen RL, Nikitin Y, Anderson C, Belhani A, Forette F. Rajkumar C, Thijs L, Banya W, Bulpitt CJ for the HYVET Study Group. Treatment of Hypertension in Patients 80 Years of Age and Older. New Eng J Med 2008;358:1887-98.

Book Chapters
O’Brien E. Assessment of the circadian cardiovascular risk with ambulatory blood pressure measurement. In European Society of Hypertension. Textbook of Hypertension. Ed. G. Mancia.Taylor and Francis.2008.pp.48-60

Editorials
O’Brien E. Ambulatory Blood Pressure Measurement Should Be a Routine Investigation in Patients with Renal Disease. European Renal Disease 2008;52-53

Staessen JA, O’Brien E. Proceedings of a workshop of the European Society of Hypertension. Blood Press Moni. 2008;13:143

Letters
Ryan AW, O’Brien E, Shields D, McManus R. Lack of association between NFKBIL1/LTA polymorphisms and hypertension, myocardial infarct, unstable angina and stable angina in a large Irish population sample. Atherosclerosis 2008;197:465–466

Adiyaman AA, Dechering DG, Thien T, Boggia J, Hanssen TW, Li Y, Wang J-G, O’Brien E , Staessen JA. Putting a spin on the ambulatory arterial stiffness index. J Hypertens 2008, 26:1266–1269 O’Brien E.

Adiyaman AA, Dechering DG, Thien T, Boggia J, Hanssen TW, Li Y, Wang J-G, O’Brien E , Staessen JA. Putting a spin on the ambulatory arterial stiffness index. J Hypertens 2008, 26:1266–1269

Response to Prevalence and Risk Factors of Masked Hypertension Identified by Multiple Self-Blood Pressure Measurement. Hypertension 2008;52;e139; originally published online Sep 29, 2008.

General and Educational
O’Brien E. CHD on the increase again: fact or fiction? Medicine Weekly 2008.Jan p.36

O’Brien E. Cardiovascular mortality. Medicine Weekly 2008.Apr p.40

O’Brien E. Stroke prevention. Irish Nursing 2008;16: Iss 3

O’Brien R. The disgrace of Ireland’s blood pressure statistics. Irish Medical Times 2008;16.05.08.p.27

O’Brien E. Ireland failing in battle against CVD. Forum 2008;May:45-48

O’Brien E. Ireland must try harder against CVD, Cardiology Professional 2008;Summer:28-30